Journal
JOURNAL OF BACTERIOLOGY
Volume 190, Issue 10, Pages 3768-3773Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.00058-08
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- Korea Institute of Marine Science & Technology Promotion (KIMST) [B10400207A290100900] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
- National Research Foundation of Korea [과C6A2206] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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The Vibrio vulnificus aphB mutant was significantly less virulent than the wild type and was impaired in motility and adherence to host cells. Microarray analysis revealed that AphB of V. vulnificus (AphB(V upsilon)) influences the expression of over 10% of the V. vulnificus genome. The combined results indicated that AphB(V upsilon) is a global regulator contributing to the pathogenesis of V. vulnificus.
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