Journal
JOURNAL OF BACTERIOLOGY
Volume 190, Issue 13, Pages 4754-4758Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.00131-08
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We observed a spontaneous amplification of the Streptomyces coelicolor chromosome, including genes encoding biosynthetic enzymes of the antibiotic actinorhodin. A new junction of two tandem segments has, inserted within it, a third copy of a transposable element existing in two places elsewhere in the chromosome, suggesting its involvement in the amplification mechanism.
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