Journal
JOURNAL OF BACTERIOLOGY
Volume 190, Issue 20, Pages 6903-6908Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.00865-08
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Funding
- Williams College
- National Institutes of Health [1 R15 GM076028-01]
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R15GM076028] Funding Source: NIH RePORTER
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The phosphopantetheinyl transferase genes SCO5883 (redU) and SCO6673 were disrupted in Streptomyces coelicolor. The redU mutants did not synthesize undecylprodigiosin, while SCO6673 mutants failed to produce calcium-dependent antibiotic. Neither gene was essential for actinorhodin production or morphological development in S. coelicolor, although their mutation could influence these processes.
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