Related references
Note: Only part of the references are listed.Differential Scales of Protein Quality Control
Suzanne Wolff et al.
CELL (2014)
LC3 Binding to the Scaffolding Protein JIP1 Regulates Processive Dynein-Driven Transport of Autophagosomes
Meng-meng Fu et al.
DEVELOPMENTAL CELL (2014)
Kinases and Pseudokinases: Lessons from RAF
Andrey S. Shaw et al.
MOLECULAR AND CELLULAR BIOLOGY (2014)
Three-dimensional structure of human γ-secretase
Peilong Lu et al.
NATURE (2014)
Day of the dead: pseudokinases and pseudophosphatases in physiology and disease
Veronika Reiterer et al.
TRENDS IN CELL BIOLOGY (2014)
Beam-induced motion correction for sub-megadalton cryo-EM particles
Sjors H. W. Scheres
ELIFE (2014)
Challenges and Opportunities in the Development of Protein Phosphatase-Directed Therapeutics
Sofie De Munter et al.
ACS CHEMICAL BIOLOGY (2013)
Allosteric Activation of Functionally Asymmetric RAF Kinase Dimers
Jiancheng Hu et al.
CELL (2013)
Ubiquitination and selective autophagy
S. Shaid et al.
CELL DEATH AND DIFFERENTIATION (2013)
Engineering A-kinase Anchoring Protein (AKAP)-selective Regulatory Subunits of Protein Kinase A (PKA) through Structure-based Phage Selection
Matthew G. Gold et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors
Meng-meng Fu et al.
JOURNAL OF CELL BIOLOGY (2013)
An MRAS, SHOC2, and SCRIB Complex Coordinates ERK Pathway Activation with Polarity and Tumorigenic Growth
Lucy C. Young et al.
MOLECULAR CELL (2013)
TRPV1 structures in distinct conformations reveal activation mechanisms
Erhu Cao et al.
NATURE (2013)
Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM
Xueming Li et al.
NATURE METHODS (2013)
AMPARs and Synaptic Plasticity: The Last 25 Years
Richard L. Huganir et al.
NEURON (2013)
Pseudophosphatase STYX modulates cell-fate decisions and cell migration by spatiotemporal regulation of ERK1/2
Veronika Reiterer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Ribosome structures to near-atomic resolution from thirty thousand cryo-EM particles
Xiao-chen Bai et al.
ELIFE (2013)
Anchored phosphatases modulate glucose homeostasis
Simon A. Hinke et al.
EMBO JOURNAL (2012)
AKAP150-Anchored Calcineurin Regulates Synaptic Plasticity by Limiting Synaptic Incorporation of Ca2+-Permeable AMPA Receptors
Jennifer L. Sanderson et al.
JOURNAL OF NEUROSCIENCE (2012)
Balanced interactions of calcineurin with AKAP79 regulate Ca2+-calcineurin-NFAT signaling
Huiming Li et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
Dynamic Regulation of Myosin Light Chain Phosphorylation by Rho-kinase
Takako Kaneko-Kawano et al.
PLOS ONE (2012)
Conformational Control of the Ste5 Scaffold Protein Insulates Against MAP Kinase Misactivation
Jesse G. Zalatan et al.
SCIENCE (2012)
RAF Inhibitor-Induced KSR1/B-RAF Binding and Its Effects on ERK Cascade Signaling
Melissa M. McKay et al.
CURRENT BIOLOGY (2011)
Acetylation Regulates Gluconeogenesis by Promoting PEPCK1 Degradation via Recruiting the UBR5 Ubiquitin Ligase
Wenqing Jiang et al.
MOLECULAR CELL (2011)
Disorder Targets Misorder in Nuclear Quality Control Degradation: A Disordered Ubiquitin Ligase Directly Recognizes Its Misfolded Substrates
Joel C. Rosenbaum et al.
MOLECULAR CELL (2011)
A Raf-induced allosteric transition of KSR stimulates phosphorylation of MEK
Damian F. Brennan et al.
NATURE (2011)
Probing cellular protein complexes using single-molecule pull-down
Ankur Jain et al.
NATURE (2011)
An entirely specific type I A-kinase anchoring protein that can sequester two molecules of protein kinase A at mitochondria
Christopher K. Means et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Architecture and dynamics of an A-kinase anchoring protein 79 (AKAP79) signaling complex
Matthew G. Gold et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Mutation that blocks ATP binding creates a pseudokinase stabilizing the scaffolding function of kinase suppressor of Ras, CRAF and BRAF
Jiancheng Hu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Scaffold Proteins: Hubs for Controlling the Flow of Cellular Information
Matthew C. Good et al.
SCIENCE (2011)
The ATAC Acetyltransferase Complex Coordinates MAP Kinases to Regulate JNK Target Genes
Tamaki Suganuma et al.
CELL (2010)
Cell Signaling by Receptor Tyrosine Kinases
Mark A. Lemmon et al.
CELL (2010)
Nonhistone protein acetylation as cancer therapy targets
Brahma N. Singh et al.
EXPERT REVIEW OF ANTICANCER THERAPY (2010)
Incidence of the V600K mutation among melanoma patients with BRAF mutations, and potential therapeutic response to the specific BRAF inhibitor PLX4032
Jill C. Rubinstein et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2010)
Interaction with AKAP79 Modifies the Cellular Pharmacology of PKC
Naoto Hoshi et al.
MOLECULAR CELL (2010)
Networking with AKAPs: Context-dependent Regulation of Anchored Enzymes
Emily J. Welch et al.
MOLECULAR INTERVENTIONS (2010)
RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF
Poulikos I. Poulikakos et al.
NATURE (2010)
RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth
Georgia Hatzivassiliou et al.
NATURE (2010)
The scaffold protein Ste5 directly controls a switch-like mating decision in yeast
Mohan K. Malleshaiah et al.
NATURE (2010)
AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade
F. Donelson Smith et al.
NATURE CELL BIOLOGY (2010)
Acetylation of Metabolic Enzymes Coordinates Carbon Source Utilization and Metabolic Flux
Qijun Wang et al.
SCIENCE (2010)
Regulation of Cellular Metabolism by Protein Lysine Acetylation
Shimin Zhao et al.
SCIENCE (2010)
Allosteric Protein Kinase Regulation by Pseudokinases: Insights from STRAD
Thanashan Rajakulendran et al.
SCIENCE SIGNALING (2010)
Structure of D-AKAP2:PKA RI Complex: Insights into AKAP Specificity and Selectivity
Ganapathy N. Sarma et al.
STRUCTURE (2010)
LKB1 and AMP-activated protein kinase control of mTOR signalling and growth
R. J. Shaw
ACTA PHYSIOLOGICA (2009)
Regulation of MBK-2/DYRK by CDK-1 and the Pseudophosphatases EGG-4 and EGG-5 during the Oocyte-to-Embryo Transition
Ken Chih-Chien Cheng et al.
CELL (2009)
Pseudophosphatases: Grab and Hold on
Nicholas K. Tonks
CELL (2009)
Docking Motif-Guided Mapping of the Interactome of Protein Phosphatase-1
Annick Hendrickx et al.
CHEMISTRY & BIOLOGY (2009)
EGG-4 and EGG-5 Link Events of the Oocyte-to-Embryo Transition with Meiotic Progression in C. elegans
Jean M. Parry et al.
CURRENT BIOLOGY (2009)
A-kinase Anchoring Proteins: From Protein Complexes to Physiology and Disease
Graeme K. Carnegie et al.
IUBMB LIFE (2009)
Adenylyl Cyclase-A-kinase Anchoring Protein Complexes: The Next Dimension in cAMP Signaling
Carmen W. Dessauer
MOLECULAR PHARMACOLOGY (2009)
Mutation of SHOC2 promotes aberrant protein N-myristoylation and causes Noonan-like syndrome with loose anagen hair
Viviana Cordeddu et al.
NATURE GENETICS (2009)
Structure of the LKB1-STRAD-MO25 Complex Reveals an Allosteric Mechanism of Kinase Activation
Elton Zeqiraj et al.
SCIENCE (2009)
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
Chunaram Choudhary et al.
SCIENCE (2009)
Cell Signaling in Space and Time: Where Proteins Come Together and When They're Apart
John D. Scott et al.
SCIENCE (2009)
ATP and MO25 alpha Regulate the Conformational State of the STRAD alpha Pseudokinase and Activation of the LKB1 Tumour Suppressor
Elton Zeqiraj et al.
PLOS BIOLOGY (2009)
Myosin phosphatase target subunit: Many roles in cell function
Fumio Matsumura et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Characterization of the role of a trimeric protein phosphatase complex in recovery from cisplatin-induced versus noncrosslinking DNA damage
Cristina Vazquez-Martin et al.
FEBS JOURNAL (2008)
Native mass spectrometry: a bridge between interactomics and structural biology
Albert J. R. Heck
NATURE METHODS (2008)
ATAC is a double histone acetyltransferase complex that stimulates nucleosome sliding
Tamaki Suganuma et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)
Loss of AKAP150 perturbs distinct neuronal processes in mice
Brian J. Tunquist et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
CELL BIOLOGY Going Global on Ubiquitin
Caroline Grabbe et al.
SCIENCE (2008)
Deregulated proteolysis by the F-box proteins SKP2 and β-TrCP:: tipping the scales of cancer
David Frescas et al.
NATURE REVIEWS CANCER (2008)
The molecular sociology of the cell
Carol V. Robinson et al.
NATURE (2007)
Integrating signals from RTKs to ERK/MAPK
M. M. McKay et al.
ONCOGENE (2007)
A mechanism for cell-cycle regulation of MAP kinase signaling in a yeast differentiation pathway
Shelly C. Strickfaden et al.
CELL (2007)
Genetic screening for signal transduction in the era of network biology
Adam Friedman et al.
CELL (2007)
Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase
Bin Zheng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Rapid chemically induced changes of Ptdlns(4,5)P2 gate KCNQ ion channels
Byung-Chang Suh et al.
SCIENCE (2006)
Molecular basis of AKAP specificity for PKA regulatory subunits
Matthew G. Gold et al.
MOLECULAR CELL (2006)
A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinase
Francis S. Kinderman et al.
MOLECULAR CELL (2006)
Dynamic regulation of cAMP synthesis through anchored PKA-Adenylyl cyclase V/VI complexes
Andrea L. Bauman et al.
MOLECULAR CELL (2006)
An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor
Xuewu Zhang et al.
CELL (2006)
Analysis of the cGMP/cAMP interactome using a chemical proteomics approach in mammalian heart tissue validates sphingosine kinase type 1-interacting protein as a genuine and highly abundant AKAP
Arjen Scholten et al.
JOURNAL OF PROTEOME RESEARCH (2006)
Compartmentation of cyclic nucleotide signaling in the heart - The role of A-kinase anchoring proteins
KL Dodge-Kafka et al.
CIRCULATION RESEARCH (2006)
A phosphatase holoenzyme comprised of Shoc2/Sur8 and the catalytic subunit of PP1 functions as an M-Ras effector to modulate Raf activity
P Rodriguez-Viciana et al.
MOLECULAR CELL (2006)
Oscillations of cyclic AMP in hormone-stimulated insulin-secreting β-cells
O Dyachok et al.
NATURE (2006)
Emerging roles of pseudokinases
Jerome Boudeau et al.
TRENDS IN CELL BIOLOGY (2006)
Distinct enzyme combinations in AKAP signalling complexes permit functional diversity
N Hoshi et al.
NATURE CELL BIOLOGY (2005)
Degradation-mediated protein quality control in the nucleus
RG Gardner et al.
CELL (2005)
Phosphotyrosine interactome of the ErbB-receptor kinase family
Waltraud X. Schulze et al.
MOLECULAR SYSTEMS BIOLOGY (2005)
AKAP signalling complexes: Focal points in space and time
W Wong et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
Localized effects of cAMP mediated by distinct routes of protein kinase A
K Tasken et al.
PHYSIOLOGICAL REVIEWS (2004)
MO25α/β interact with STRADα/β enhancing their ability to bind, activate and localize LKB1 in the cytoplasm
J Boudeau et al.
EMBO JOURNAL (2003)
AKAP150 signaling complex promotes suppression of the M-current by muscarinic agonists
N Hoshi et al.
NATURE NEUROSCIENCE (2003)
The JNK-interacting protein-1 scaffold protein targets MAPK phosphatase-7 to dephosphorylate JNK
EA Willoughby et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Mass spectrometry-based proteomics
R Aebersold et al.
NATURE (2003)
Regulation of map kinase signaling modules by scaffold proteins in mammals
DK Morrison et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY (2003)
The protein kinase complement of the human genome
G Manning et al.
SCIENCE (2002)
Evolution of protein kinase signaling from yeast to man
G Manning et al.
TRENDS IN BIOCHEMICAL SCIENCES (2002)
Combinatorial control of protein phosphatase-1
M Bollen
TRENDS IN BIOCHEMICAL SCIENCES (2001)
Targeted protein kinase A and PP-2B regulate insulin secretion through reversible phosphorylation
LB Lester et al.
ENDOCRINOLOGY (2001)
Mutational analysis suggests that activation of the yeast pheromone response mitogen-activated protein kinase pathway involves conformational changes in the Ste5 scaffold protein
C Sette et al.
MOLECULAR BIOLOGY OF THE CELL (2000)
Cell communication: The inside story
JN Scott et al.
SCIENTIFIC AMERICAN (2000)
Share Paper
