Journal
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY
Volume 12, Issue 5, Pages 259-270Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrgastro.2015.49
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Funding
- Insituto de Salud Carlos III [PI14/00453]
- Collegi Oficial de Farmaceutics de Barcelona
- Agencia de Gestio d'Ajuts Universitaris i de Recerca [2014 SGR 789]
- Fundacio Agrupacio Mutua, Academia de Ciencies Mediques i de la Salut de Catalunya i de Balears
- Fundacio La Marato TV3 [exp 112310]
- Spanish Ministerio de Economia y Competitividad
- CIBERehd
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Dysphagia is a symptom of swallowing dysfunction that occurs between the mouth and the stomach. Although oropharyngeal dysphagia is a highly prevalent condition (occurring in up to 50% of elderly people and 50% of patients with neurological conditions) and is associated with aspiration, severe nutritional and respiratory complications and even death, most patients are not diagnosed and do not receive any treatment. By contrast, oesophageal dysphagia is less prevalent and less severe, but with better recognized symptoms caused by diseases affecting the enteric nervous system and/or oesophageal muscular layers. Recognition of the clinical relevance and complications of oesophageal and oropharyngeal dysphagia is growing among health-care professionals in many fields. In addition, the emergence of new methods to screen and assess swallow function at both the oropharynx and oesophagus, and marked advances in understanding the pathophysiology of these conditions, is paving the way for a new era of intensive research and active therapeutic strategies for affected patients. Indeed, a unified field of deglutology is developing, with new professional profiles to cover the needs of all patients with dysphagia in a nonfragmented way.
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