Journal
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY
Volume 12, Issue 3, Pages 125-U19Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrgastro.2015.22
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Funding
- NCATS NIH HHS [U18 TR000546] Funding Source: Medline
- NIDDK NIH HHS [U24 DK085532, R01 DK092456, U01 DK085532, U01 DK103117, R01 DK098350] Funding Source: Medline
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The stem cells in the stomach and intestine are regulated by different signalling pathways and give rise to entirely different specialized lineages. A study by Simmini and colleagues suggests that the organ-specific identity of gastrointestinal stem cells is regulated by one transcription factor, Cdx2.
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