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Characterization of the pH of folate receptor-containing endosomes and the rate of hydrolysis of internalized acid-labile folate-drug conjugates
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Drug penetration in solid tumours
Andrew I. Minchinton et al.
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Tumour microenvironment - Opinion - Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy
CM Overall et al.
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Targeting an MMP-9-activated prodrug to multiple myeloma-diseased bone marrow: a proof of principle in the 5T33MM mouse model
E Van Valckenborgh et al.
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HER2-Mediated internalization of a targeted prodrug cytotoxic conjugate is dependent on the valency of the targeting ligand
V Guillemard et al.
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Folate receptor expression in carcinomas and normal tissues determined by a quantitative radioligand binding assay
N Parker et al.
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Bispecific minibodies targeting HER2/neu and CD16 exhibit improved tumor lysis when placed in a divalent tumor antigen binding format
LS Shahied et al.
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Ligand binding and kinetics of folate receptor recycling in vivo: Impact on receptor-mediated drug delivery
CM Paulos et al.
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Binding and interstitial penetration of liposomes within avascular tumor spheroids
K Kostarelos et al.
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ONCOMINE: A cancer microarray database and integrated data-mining platform
DR Rhodes et al.
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JM Saul et al.
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CP Leamon et al.
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Ligand-targeted therapeutics in anticancer therapy
TM Allen
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Openings between defective endothelial cells explain tumor vessel leakiness
H Hashizume et al.
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Sigma-2 receptors as a biomarker of proliferation in solid tumours
KT Wheeler et al.
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