Journal
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
Volume 16, Issue 5, Pages 542-548Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020.2014.911290
Keywords
Bruguiera gymnorrhiza; mangrove fungus; Penicillium sclerotiorum; 2; 5-dioxopiperazine; alkaloid
Funding
- National Marine 863 Projects [2011AA09070102, 2013AA092902]
- Natural Science Foundation of China [21021063, 81273430, 21072204, 81302692]
- SKLDR/SIMM Project [SIMM1203ZZ-03]
- EU 7th Framework Program-IRSES Project [246987]
Ask authors/readers for more resources
One new naturally occurring 7-membered 2,5-dioxopiperazine alkaloid named (+)-cyclopenol (1), along with nine known compounds including viridicatol (2), 3-(dimethylaminomethyl)-1-(1,1-dimethyl-2-propenyl)indole (3), anacine (4), aurantiomide C (5), viridicatin (6), 3-O-methylviridicatin (7), verrucosidin (8), ergosterol (9), and ergosterol peroxide (10), was isolated from the EtOAc extract of fungus Penicillium sclerotiorum, an endophytic fungal strain isolated from Chinese mangrove Bruguiera gymnorrhiza. The chemical structure of the new compound 1 was elucidated on the basis of detailed spectroscopic analysis. The absolute configuration of 1 was determined by single-crystal X-ray analysis with Cu K radiation (=1.54178 angstrom). To our knowledge, (+)-cyclopenol (1) represents the first example of 7-membered 2,5-dioxopiperazine isolated from mangrove endophytic fungus.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available