Journal
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
Volume 16, Issue 1, Pages 11-19Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020.2013.875011
Keywords
Rehmannia glutinosa; ionone glucoside; hepatoprotective
Funding
- National Science and Technology Project of China [2011ZX09307-002-01]
- State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences
- Peking Union Medical College
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Four new ionone and ionone glycosides (1-4), and a new monoterpene (5), together with 10 known analogues (6-15), were isolated from the air-dried roots of Rehmannia glutinosa. The structures of these compounds were elucidated on the basis of spectroscopic data analysis. Furthermore, in in vitro assays, compound 3 (10M) exhibited moderate hepatoprotective activities against d-galactosamine-induced HL-7702 cell damage. [GRAPHICS] .
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