Journal
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
Volume 16, Issue 12, Pages 1119-1125Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020.2014.951924
Keywords
Rutaceae; nitric oxide production; phenolic glycosides; Glycosmis pentaphylla
Funding
- Natural Science Foundation of Hubei Province, China [2013CFB450, 2013CFA013]
- National Key Technology R&D Program in the 12th Five Year Plan of China [2012BAI27B06]
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Three new phenolic glycosides, named as glycopentosides A-C (1-3), along with nine known compounds were isolated from the n-BuOH extract of stems of Glycosmis pentaphylla. Their structures were determined by using spectroscopic and chemical methods. Bioassay showed that compound 10 (tachioside) could inhibit nitric oxide production in lipopolysaccharides-stimulated RAW 264.7 cells with IC50 value of 12.14 mu M.
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