4.4 Article

A new triterpenoid saponin from Gymnema sylvestre

Journal

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
Volume 14, Issue 12, Pages 1186-1190

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020.2012.726517

Keywords

Gymnema sylvestre; triterpenoid saponin; Asclepiadaceae

Funding

  1. International Science & Technology Cooperation Program of China [2010DFB33260]
  2. Beijing Municipal Education Commission [NCET-080746]
  3. Program for New Century Excellent Talents in University [NCET-080746]
  4. Program for the Development of Scientific and Technological Plan of Jilin [20100122]

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Besides four known compounds, a new triterpenoid saponin was isolated from the stems of Gymnema sylvestre. The structure of the new triterpenoid saponin was established as 3 beta,16 beta,22 alpha-trihydroxy-olean-12-ene 3-O-beta-D-xylopyranosyl-(1 --> 6)-beta-D-glucopyranosyl-(1 --> 6)-beta-D-glucopyranoside (1) on the basis of 1D and 2D NMR techniques, including COSY, HMBC, HMQC, and NOESY correlations. Four known compounds 2, 3, 4, and 5 were identified on the basis of spectroscopic data.

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