Journal
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
Volume 14, Issue 5, Pages 450-456Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020.2012.669578
Keywords
Nicotiana tabacum; phenolic compounds; nicotphenols A-C; anti-HIV-1 activities; cytotoxicities
Funding
- Excellent Scientific and Technological Team of Yunnan [2009CI014]
- Natural Science Foundation of Yunnan Province [2008B0042Q]
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Three new phenolic compounds, nicotphenols A-C (1-3), together with 14 known phenols (4-17), were isolated from the leaves of Nicotiana tabacum. Their structures were established by means of spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds 1-3 were tested for their anti-HIV-1 activities and cytotoxicities. They all showed significant cytotoxic abilities and modest anti-HIV-1 activities, respectively.
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