4.4 Article

A new acyclic thiophene sesterterpene from the Sikao Bay sponge, Xestospongia sp.

Journal

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
Volume 13, Issue 9, Pages 879-883

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020.2011.591386

Keywords

acyclic sesterterpene; thiophene; Xestospongia sp.

Funding

  1. Thailand Research Fund [MRG5080328]
  2. Commission on Higher Education, Thailand

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Bioactivity-guided fractionation of the ethyl acetate extract of a marine sponge, Xestospongia sp., led to the isolation of a new thiophene-S-oxide acyclic sesterterpene (1). The chemical structure was extensively analyzed using NMR and mass spectral data. Compound 1 showed weak cytotoxicity against Vero cells.

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