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JOURNAL OF LIPID RESEARCH (2007)
Co-receptor requirements for fibroblast growth factor-19 signaling
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JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Tissue-specific expression of βKlotho and fibroblast growth factor (FGF) receptor Isoforms determines metabolic activity of FGF19 and FGF21
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JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Liver-specific activities of FGF19 require Klotho beta
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JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
PPARα is a key regulator of hepatic FGF21
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Lithocholic acid induction of the FGF19 promoter in intestinal cells is mediated by PXR
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WORLD JOURNAL OF GASTROENTEROLOGY (2007)
Hepatic fibroblast growth factor 21 is regulated by PPARα and is a key mediator of hepatic lipid metabolism in ketotic states
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CELL METABOLISM (2007)
Endocrine regulation of the fasting response by PPARα-mediated induction of fibroblast growth factor 21
Takeshi Inagaki et al.
CELL METABOLISM (2007)
Klotho spins the thread of fife -: what does Klotho do to the receptors of fibroblast growth factor-23 (FGF23)?
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NEPHROLOGY DIALYSIS TRANSPLANTATION (2007)
βKlotho is required for metabolic activity of fibroblast growth factor 21
Yasushi Ogawa et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members
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MOLECULAR AND CELLULAR BIOLOGY (2007)
FGF23 concentrations vary with disease status in autosomal dominant hypophosphatemic rickets
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JOURNAL OF BONE AND MINERAL RESEARCH (2007)
1,25-dihydroxyvitamin D3/VDR-mediated induction of FGF23 as well as transcriptional control of other bone anabolic and catabolic genes that orchestrate the regulation of phosphate and calcium mineral metabolism
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JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2007)
Ablation of vitamin D signaling rescues bone, mineral, and glucose homeostasis in Fgf-23 deficient mice
Martina Hesse et al.
MATRIX BIOLOGY (2007)
The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21
Alexei Kharitonenkov et al.
ENDOCRINOLOGY (2007)
Klotho converts canonical FGF receptor into a specific receptor for FGF23
Itaru Urakawa et al.
NATURE (2006)
Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man
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JOURNAL OF INTERNAL MEDICINE (2006)
Identification of a hormonal basis for gallbladder filling
Mihwa Choi et al.
NATURE MEDICINE (2006)
Hypervitaminosis D and premature aging:: lessons learned from Fgf23 and Klotho mutant mice
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TRENDS IN MOLECULAR MEDICINE (2006)
Receptor specificity of the fibroblast growth factor family - The complete mammalian FGF family
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JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Regulation of fibroblast growth factor-23 signaling by Klotho
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JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Fibroblast growth factor-21 improves pancreatic beta-cell function and survival by activation of extracellular signal-regulated kinase 1/2 and Akt signaling pathways
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DIABETES (2006)
1α,25-Dihydroxyvitamin D3 upregulates FGF23 gene expression in bone:: the final link in a renal-gastrointestinal-skeletal axis that controls phosphate transport
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AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2005)
Vitamin D receptor-independent FGF23 actions in regulating phosphate and vitamin D metabolism
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AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2005)
Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis
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CELL METABOLISM (2005)
Impaired negative feedback suppression of bile acid synthesis in mice lacking βKlotho
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JOURNAL OF CLINICAL INVESTIGATION (2005)
Genetic dissection of phosphate- and vitamin D-mediated regulation of circulating Fgf23 concentrations
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BONE (2005)
FGF-21 as a novel metabolic regulator
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JOURNAL OF CLINICAL INVESTIGATION (2005)
Independent repression of bile acid synthesis and activation of c-Jun N-terminal kinase (JNK) by activated hepatocyte fibroblast growth factor receptor 4 (FGFR4) and bile acids
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JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Structural basis for fibroblast growth factor receptor activation
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CYTOKINE & GROWTH FACTOR REVIEWS (2005)
FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis
T Shimada et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2004)
FGF-23 transgenic mice demonstrate hypophosphatemic rickets with reduced expression of sodium phosphate cotransporter type IIa
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism
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JOURNAL OF CLINICAL INVESTIGATION (2004)
Regulation of bile acid synthesis under reconstructed enterohepatic circulation in rats
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STEROIDS (2004)
Transgenic mice overexpressing human fibroblast growth factor 23 (R176Q) delineate a putative role for parathyroid hormone in renal phosphate wasting disorders
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ENDOCRINOLOGY (2004)
Evolution of the Fgf and Fgfr gene families
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TRENDS IN GENETICS (2004)
Fibroblast growth factor 19 increases metabolic rate I and reverses dietary and leptlin-deficient diabetes
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ENDOCRINOLOGY (2004)
Mouse FGF15 is the ortholog of human and chick FGF19, but is not uniquely required for otic induction
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DEVELOPMENTAL BIOLOGY (2004)
Regulation of fibroblastic growth factor 23 expression but not degradation by PHEX
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis
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GENES & DEVELOPMENT (2003)
Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia.
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NEW ENGLAND JOURNAL OF MEDICINE (2003)
Increased circulatory level of biologically active full-length FGF-23 in patients with hypophosphatemic rickets/osteomalacia
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JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2002)
A mouse model of hepatocellular carcinoma - Ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic mice
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AMERICAN JOURNAL OF PATHOLOGY (2002)
Diabetes mellitus and genetically programmed defects in β-cell function
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NATURE (2001)
Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23
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KIDNEY INTERNATIONAL (2001)
Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Identification of a novel fibroblast growth factor, FGF-23, preferentially expressed in the ventrolateral thalamic nucleus of the brain
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
Identification of a novel FGF, FGF-21, preferentially expressed in the liver
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BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION (2000)
Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4
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JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
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