4.5 Article Retracted Publication

被撤回的出版物: Oxidative stress induced by aluminum oxide nanomaterials after acute oral treatment in Wistar rats (Retracted article. See vol. 43, pg. 615, 2023)

Journal

JOURNAL OF APPLIED TOXICOLOGY
Volume 32, Issue 6, Pages 436-445

Publisher

WILEY
DOI: 10.1002/jat.1775

Keywords

Aluminium oxide nanomaterials; acute oral toxicity; oxidative stress; antioxidant enzymes; histopathology; Wistar rat

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Funding

  1. Department of Biotechnology (DBT), New Delhi

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This study investigated the oxidative stress induced after acute oral treatment with 500, 1000 and 2000?mg kg-1 doses of Al2O3-30 and -40?nm and bulk Al2O3 in Wistar rats. Both the nanomaterials induced significant oxidative stress in a dose-dependent manner in comparison to the bulk. There was no significant difference between the two nanomaterials. However, the effect decreased with increase with time after treatment. The histopathological examination showed lesions only in liver with Al2O3 nanomaterials at 2000?mg kg-1. Copyright (C) 2011 John Wiley & Sons, Ltd.

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