Journal
JOURNAL OF APPLIED POLYMER SCIENCE
Volume 118, Issue 6, Pages 3197-3202Publisher
WILEY
DOI: 10.1002/app.32758
Keywords
biomimetic; block copolymers; self-assembly; vesicles
Categories
Funding
- Natural Science Foundation of China [NSFC-20774082, 50830106]
- 863 National High-Tech RD Program [2006AA03Z329, 2006AA03Z444]
- Ph.D. Programs Foundation of Ministry of Education [20070335024]
- NSFC-ZJ [Y4080250]
- Science Foundation of Chinese University
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The poly(2-methacryloyloxyethyl phosphorylcholine)-block-poly(D,L-lactide) (PMPC-b-PLA) was specially designed to develop biomimetic giant vesicles (GVs) and giant large compound vesicles via a simple spontaneous assemble in aqueous solution. The weight fraction of the hydrophilic PMPC block (f(PC)) was proved to play an important role in the size and morphology control of the self-assembled aggregates. The GVs with controlled micrometer size and biomimetic PMPC corona have great potential as artificial cell models. (C) 2010 Wiley Periodicals, Inc. J Appl Polym Sci.118: 3197-3202, 2010
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