Journal
NATURE IMMUNOLOGY
Volume 16, Issue 6, Pages 596-597Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ni.3174
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Funding
- NIAMS NIH HHS [R01 AR056296] Funding Source: Medline
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The anti-inflammatory molecule A20 inhibits necroptotic cell death by inhibiting ubiquitination of the kinase RIPK3 at the Lys5 residue and preventing excessive formation of the RIPK1-RIPK3 necroptotic complex.
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