Journal
JOURNAL OF APPLIED PHYSIOLOGY
Volume 116, Issue 5, Pages 478-485Publisher
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/japplphysiol.01013.2013
Keywords
altitude; hypobaric hypoxia; pulmonary disease; cardiovascular disease
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Travel is more affordable and improved high-altitude airports, railways, and roads allow rapid access to altitude destinations without acclimatization. The physiology of exposure to altitude has been extensively described in healthy individuals; however, there is a paucity of data pertaining to those who have reduced reserve. This Physiology in Medicine article discusses the physiological considerations relevant to the safe travel to altitude and by commercial aircraft in patients with pulmonary and/or cardiac disease.
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