4.8 Article

Recombination affects accumulation of damaging and disease-associated mutations in human populations

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

The Relation between Recombination Rate and Patterns of Molecular Evolution and Variation in Drosophila melanogaster

Jose L. Campos et al.

MOLECULAR BIOLOGY AND EVOLUTION (2014)

Article Genetics & Heredity

The deleterious mutation load is insensitive to recent population history

Yuval B. Simons et al.

NATURE GENETICS (2014)

Article Biochemistry & Molecular Biology

ClinVar: public archive of relationships among sequence variation and human phenotype

Melissa J. Landrum et al.

NUCLEIC ACIDS RESEARCH (2014)

Article Multidisciplinary Sciences

High-Resolution Genomic Analysis of Human Mitochondrial RNA Sequence Variation

Alan Hodgkinson et al.

SCIENCE (2014)

Article Genetics & Heredity

SLiM: Simulating Evolution with Selection and Linkage

Philipp W. Messer

GENETICS (2013)

Article Public, Environmental & Occupational Health

Cohort profile of the CARTaGENE study: Quebec's population-based biobank for public health and personalized genomics

Philip Awadalla et al.

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY (2013)

Letter Biochemical Research Methods

Improved whole-chromosome phasing for disease and population genetic studies

Olivier Delaneau et al.

NATURE METHODS (2013)

Article Biochemistry & Molecular Biology

WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013

Jing Wang et al.

NUCLEIC ACIDS RESEARCH (2013)

Article Multidisciplinary Sciences

Integrative Annotation of Variants from 1092 Humans: Application to Cancer Genomics

Ekta Khurana et al.

SCIENCE (2013)

Review Genetics & Heredity

The Effects of Deleterious Mutations on Evolution at Linked Sites

Brian Charlesworth

GENETICS (2012)

Article Evolutionary Biology

Molecular Evolution in Nonrecombining Regions of the Drosophila melanogaster Genome

Jose L. Campos et al.

GENOME BIOLOGY AND EVOLUTION (2012)

Article Multidisciplinary Sciences

An integrated map of genetic variation from 1,092 human genomes

David M. Altshuler et al.

NATURE (2012)

Article Multidisciplinary Sciences

An Abundance of Rare Functional Variants in 202 Drug Target Genes Sequenced in 14,002 People

Matthew R. Nelson et al.

SCIENCE (2012)

Article Biochemistry & Molecular Biology

Recombination Modulates How Selection Affects Linked Sites in Drosophila

Suzanne E. McGaugh et al.

PLOS BIOLOGY (2012)

Article Multidisciplinary Sciences

The landscape of recombination in African Americans

Anjali G. Hinch et al.

NATURE (2011)

Article Multidisciplinary Sciences

Classic Selective Sweeps Were Rare in Recent Human Evolution

Ryan D. Hernandez et al.

SCIENCE (2011)

Article Multidisciplinary Sciences

Deep Human Genealogies Reveal a Selective Advantage to Be on an Expanding Wave Front

Claudia Moreau et al.

SCIENCE (2011)

Article Biochemical Research Methods

Haplotype allelic classes for detecting ongoing positive selection

Julie Hussin et al.

BMC BIOINFORMATICS (2010)

Article Multidisciplinary Sciences

Fine-scale recombination rate differences between sexes, populations and individuals

Augustine Kong et al.

NATURE (2010)

Letter Biochemical Research Methods

A method and server for predicting damaging missense mutations

Ivan A. Adzhubei et al.

NATURE METHODS (2010)

Article Biochemical Research Methods

Identifying a High Fraction of the Human Genome to be under Selective Constraint Using GERP plus

Eugene V. Davydov et al.

PLOS COMPUTATIONAL BIOLOGY (2010)

Article Biochemical Research Methods

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

Prateek Kumar et al.

NATURE PROTOCOLS (2009)

Article Genetics & Heredity

The effects of deleterious mutations on evolution in non-recombining genomes

Vera B. Kaiser et al.

TRENDS IN GENETICS (2009)

Article Biochemical Research Methods

A flexible forward simulator for populations subject to selection and demography

Ryan D. Hernandez

BIOINFORMATICS (2008)

Article Biochemistry & Molecular Biology

No effect of recombination on the efficacy of natural selection in primates

Kevin Bullaughey et al.

GENOME RESEARCH (2008)

Article Genetics & Heredity

Assessing the evolutionary impact of amino acid mutations in the human genome

Adam R. Boyko et al.

PLOS GENETICS (2008)

Article Multidisciplinary Sciences

A second generation human haplotype map of over 3.1 million SNPs

Kelly A. Frazer et al.

NATURE (2007)

Article Multidisciplinary Sciences

Interference among deleterious mutations favours sex and recombination in finite populations

Peter D. Keightley et al.

NATURE (2006)

Article Biochemistry & Molecular Biology

Sequence features in regions of weak and strong linkage disequilibrium

AV Smith et al.

GENOME RESEARCH (2005)

Article Biochemistry & Molecular Biology

Why do human diversity levels vary at a megabase scale?

I Hellmann et al.

GENOME RESEARCH (2005)

Article Biochemistry & Molecular Biology

The PANTHER database of protein families, subfamilies, functions and pathways

HY Mi et al.

NUCLEIC ACIDS RESEARCH (2005)

Article Genetics & Heredity

Human SNP variability and mutation rate are higher in regions of high recombination

MJ Lercher et al.

TRENDS IN GENETICS (2002)

Article Biology

The degeneration of Y chromosomes

B Charlesworth et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2000)