4.8 Editorial Material

A mammalian pexophagy target

Journal

NATURE CELL BIOLOGY
Volume 17, Issue 11, Pages 1371-1373

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/ncb3253

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Funding

  1. NIDDK NIH HHS [DK41737, R37 DK041737, R56 DK041737, R01 DK041737] Funding Source: Medline

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Protein ubiquitylation in mammals is known to trigger selective autophagy of peroxisomes through a process termed pexophagy. The physiological peroxisomal target for pexophagy-related ubiquitylation has been controversial, but two studies have now identified the protein PEX5 as the real candidate.

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