Journal
NATURE
Volume 528, Issue 7580, Pages 84-+Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nature15736
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Funding
- Novartis Institutes for BioMedical Research
- Wellcome Trust [086357, 102696]
- National Institutes of Health [1U54HG006097-01]
- Novartis
- Dr. Miriam and Sheldon Adelson Medical Research Foundation
- Slim Foundation
- EMBL-EBI
- Wellcome Trust Sanger Institute Post-Doctoral (ESPOD) programme
- Cancer Research UK Clinician Scientist Fellowship [A16629]
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Large cancer cell line collections broadly capture the genomic diversity of human cancers and provide valuable insight into anti-cancer drug response. Here we show substantial agreement and biological consilience between drug sensitivity measurements and their associated genomic predictors from two publicly available large-scale pharmacogenomics resources: The Cancer Cell Line Encyclopedia and the Genomics of Drug Sensitivity in Cancer databases.
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