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Building the foundation for genomics in precision medicine

Journal

NATURE
Volume 526, Issue 7573, Pages 336-342

Publisher

NATURE PORTFOLIO
DOI: 10.1038/nature15816

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Funding

  1. NIH [U41HG006834, U01HG006500, U19HD077671]

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Precision medicine has the potential to profoundly improve the practice of medicine. However, the advances required will take time to implement. Genetics is already being used to direct clinical decision-making and its contribution is likely to increase. To accelerate these advances, fundamental changes are needed in the infrastructure and mechanisms for data collection, storage and sharing. This will create a continuously learning health-care system with seamless cycling between clinical care and research. Patients must be educated about the benefits of sharing data. The building blocks for such a system are already forming and they will accelerate the adoption of precision medicine.

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