Journal
JOURNAL OF APPLIED MICROBIOLOGY
Volume 117, Issue 2, Pages 303-319Publisher
WILEY
DOI: 10.1111/jam.12521
Keywords
lactobacilli; mechanism; mucosal immune system; probiotics; systemic immune system
Categories
Funding
- Ministry of External Affairs (Government of India)
- African Union
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The mechanism by which probiotic lactobacilli affect the immune system is strain specific. As the immune system is a multicompartmental system, each strain has its way to interact with it and induce a visible and quantifiable effect. This review summarizes the interplay existing between the host immune system and probiotic lactobacilli, that is, with emphasis on lactobacilli as a prototype probiotic genus. Several aspects including the bacterial-host crosstalk with the mucosal and systemic immune system are presented, as well as short sections on the competing effect towards pathogenic bacteria and their uses as delivery vehicle for antigens.
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