4.4 Article

A new ellagic acid derivative from Polygonum runcinatum

Journal

NATURAL PRODUCT RESEARCH
Volume 29, Issue 9, Pages 795-799

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2014.986727

Keywords

Polygonum runcinatum; antioxidant activity; ellagic acid derivative; chemical constituents

Funding

  1. National New Drug Innovation Major Project of China [2011ZX09307-002-02]
  2. Qing Lan Project of Jiangsu Province

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A new ellagic acid derivative, 3,3 '-dimethylellagic acid-4 '-O-(6 ''-galloyl)-beta-d-glucoside, named runcinatside (5), together with four known compounds 3,3 '-dimethylellagic acid (1), 3,3 ',4 '-trimethylellagic acid (2), 3,3 '-dimethylellagic acid-4 '-O-beta-d-glucoside (3) and 3-methylellagic acid-4 '-O-alpha-l-rhamno-pyranoside (4), was isolated from the roots of Polygonum runcinatum Buch.-Ham. ex D.Don Var. sinense Hemsl and the structures of these compounds were established by spectroscopic methods and comparison with previously reported data. All compounds showed antioxidant activities in vitro and compound 5 possessed the highest activity.

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