4.4 Article

New flavonoid glycosides and other chemical constituents from Clerodendrum phlomidis leaves: isolation and characterisation

Journal

NATURAL PRODUCT RESEARCH
Volume 29, Issue 19, Pages 1850-1856

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2015.1009457

Keywords

Clerodendrum phlomidis; flavonoid glycosides; 2D NMR (HSQC; HMBC; COSY; NOESY)

Funding

  1. Council of Scientific and Industrial Research (CSIR) Government of India
  2. Emeritus Scientist grant from CSIR, India

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Phytochemical investigation of the plant Clerodendrum phlomidis Linn. F. (Lamiaceae) has now led to the isolation of two new flavonoid glycosides (1, 2) together with six known compounds identified as pectolinaringenin (3), pectolinaringenin-7-O--d-glucopyranoside (4), 24-ethylcholesta-5,22E,25-triene-3-ol (5), 24-ethylcholesta-5,22E,25-triene-3-O--D-glucopyranoside (6), (2S,3S,4R,10E)-2-[(2R)-2-hydroxytetracosanoylamino]-10-octadecene-1,3,4-triol (7) and andrographolide (8) mainly by spectroscopic analysis. Compounds 4 and 6-8 are reported for the first time from C. phlomidis.

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