Journal
NATURAL PRODUCT RESEARCH
Volume 29, Issue 23, Pages 2223-2225Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2014.1003134
Keywords
endophyte; secondary metabolites; Streptomyces albolongus;2-pyrrol formic acid; antimicrobial activity
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Funding
- Sichuan provincial science and technology department [2012JY0117]
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We isolated Streptomyces sp. K15 from the root tissue of Houttuynia cordata Thunb and found that some of its secondary metabolites exhibited significant antimicrobial activity against Botrytis cinerea. Moreover, we separated, purified and identified the major active ingredient to be 2-pyrrol formic acid by using silica gel column chromatography, high-performance liquid chromatography and NMR analysis of the spectral data. 2-Pyrrol formic acid critically inhibited the growth of some phytopathogenic bacteria. Therefore, it has potential value in agricultural applications.
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