Journal
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Volume 67, Issue 10, Pages 2307-2308Publisher
OXFORD UNIV PRESS
DOI: 10.1093/jac/dks247
Keywords
bacterial genomics; microbiology; infection control; antimicrobial resistance
Funding
- UKCRC Translational Infection Research Initiative (TIRI)
- Medical Research Council [G1000803]
- Biotechnology and Biological Sciences Research Council
- National Institute for Health Research on behalf of the Department of Health
- Chief Scientist Office of the Scottish Government Health Directorate
- Health Protection Agency
- NIHR Cambridge Biomedical Research Centre
- MRC [G1000803] Funding Source: UKRI
- Medical Research Council [G1000803] Funding Source: researchfish
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The ability to perform rapid, high-throughput whole-genome sequencing using bench-top platforms represents a step-change in capabilities for diagnostic and public health microbiology laboratories. As the cost of sequencing continues to decline, the challenge will be to define when and where to apply this technology. This article reviews its potential applications in the clinical microbiology laboratory and discusses the current barriers to implementation.
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