Journal
NATURAL PRODUCT RESEARCH
Volume 30, Issue 11, Pages 1305-1308Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2015.1054284
Keywords
Zea mays; DIMBOA; antioxidant; antimicrobial; FRAP; ABTS; DPPH
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Funding
- Wroclaw Medical University [ST-763]
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The aim of this study was to evaluate the in vitro antioxidant and antimicrobial properties of the natural cyclic hydroxamic acid: 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one (DIMBOA). Antioxidant activity of the isolated DIMBOA was examined using DPPH, FRAP and ABTS tests. It was found that DIMBOA exhibits a potent free-radical scavenging activity and a weaker iron (III) ions reducing activity. Antimicrobial activity against selected G(+), G(-) bacterial strains and against yeasts-like reference strains of fungi was investigated using disk-diffusion method. It has been shown that DIMBOA possess growth inhibitory properties against many strains of studied bacteria and fungi, such as Staphylococcus aureus, Escherichia coli as well as against Saccharomyces cerevisiae.
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