Journal
NATURAL PRODUCT RESEARCH
Volume 30, Issue 3, Pages 311-315Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2015.1057730
Keywords
Sesamum indicum; Pedaliaceae; 3-epibartogenic acid; -amylase
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Funding
- Vietnam National Foundation for Science and Technology Development [NAFOSTED-104.01-2011.54]
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Two new and one known compounds were isolated from the methanol extract of Sesamum indicum leaves. By means of spectroscopic methods, their structures were elucidated and identified to be 3-epibartogenic acid (1), kaempferol 3-O-[2-O-(trans-p-coumaroyl)-3-O--L-rhamnopyranosyl]--d-glucopyranoside (2) and epigallocatechin (3). Compound 1 and 3 strongly inhibited -amylase with the IC50 values of 146.7 and 303.9M, respectively, in comparison with acarbose (IC50 124.0M).
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