Journal
NATURAL PRODUCT RESEARCH
Volume 30, Issue 17, Pages 1980-1983Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2015.1095747
Keywords
Cyclo(L-Pro-L-Tyr); cyclo(D-Pro-L-Tyr); Streptomyces; phytopathogenic bacteria
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Funding
- Center of Excellence for Innovation in Chemistry (PERCH-CIC), Office of the Higher Education Commission, Ministry of Education
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Two bioactive cyclic dipeptides, cyclo(L-Pro-L-Tyr) and cyclo(D-Pro-L-Tyr), were isolated from the culture broth of Streptomyces sp. strain 22-4 and tested against three economically important plant pathogens, Xanthomonas axonopodis pv. citri, Ralstonia solanacearum and Clavibacter michiganensis. Both cyclic dipeptides were active against X. axonopodis pv. citri and R. Solanacearum with MIC of 31.25g/mL. No activity could be observed against C. michiganensis. [GRAPHICS] .
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