Journal
NATURAL PRODUCT REPORTS
Volume 32, Issue 7, Pages 904-936Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5np00010f
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Funding
- Max Planck Society
- German Science Foundation [DFG KA2846/2-1]
- Swiss National Science Foundation [P300P3_151134]
- Swiss National Science Foundation (SNF) [P300P3_151134] Funding Source: Swiss National Science Foundation (SNF)
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Many organisms team up with microbes for defense against predators, parasites, parasitoids, or pathogens. Here we review the described protective symbioses between animals (including marine invertebrates, nematodes, insects, and vertebrates) and bacteria, fungi, and dinoflagellates. We focus on associations where the microbial natural products mediating the protective activity have been elucidated or at least strong evidence for the role of symbiotic microbes in defense is available. In addition to providing an overview of the known defensive animal-microbe symbioses, we aim to derive general patterns on the chemistry, ecology, and evolution of such associations.
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