Journal
JOURNAL OF ANTIBIOTICS
Volume 67, Issue 5, Pages 401-403Publisher
JAPAN ANTIBIOTICS RESEARCH ASSOC
DOI: 10.1038/ja.2014.6
Keywords
alpha-pyrone derivatives; antibacterial activities; mangrove endophytic fungus; Stemphylium sp.
Funding
- National Natural Science Foundation of China [21162009, 31360069]
- 973 Program
- Ministry of Science and Technology of China [2011CB512010]
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Two new (x-pyrone derivatives, infectopyrones A (1) and B (2), were obtained from the Et0Ac extract of the endophytic fungus Stemphylium sp. 33231 isolated from the mangrove Brguiera sexangula var. rhynchopetala collected in the South China Sea. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. Compounds 1 and 2 were evaluated for their antibacterial activities, and they had a broad spectrum of antibacterial activity against five terrestrial pathogenic bacteria.
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