Journal
JOURNAL OF ANTIBIOTICS
Volume 61, Issue 11, Pages 680-682Publisher
JAPAN ANTIBIOTICS RESEARCH ASSOC
DOI: 10.1038/ja.2008.96
Keywords
Actinobacteria; antibiotic; aurachin; quinoline; Rhodococcus
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A new quinoline antibiotic, aurachin RE, was isolated and identified from a culture broth of Rhodococcus erythropolis JCM 6824. The aurachin RE structure was determined based on NMR and mass spectrometric analysis. The structure is similar to that of aurachin C antibiotics that have been identified from Stigmatella aurantiaca. Compared to aurachin C, however, aurachin RE exhibits a wide and strong antimicrobial spectrum against both high- and low-GC Gram-positive bacteria.
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