4.5 Article

Arthrinic acid, a novel antifungal polyhydroxyacid from Arthrinium phaeospermum

Journal

JOURNAL OF ANTIBIOTICS
Volume 61, Issue 8, Pages 515-517

Publisher

JAPAN ANTIBIOTICS RESEARCH ASSOC
DOI: 10.1038/ja.2008.69

Keywords

antifungal; arthrinic acid; Arthrinium; structure elucidation; fungus

Funding

  1. New Zealand Foundation for Research Science and Technology [BIDX0201]
  2. Syngenta plc. Maureen Fletcher
  3. Landcare New Zealand

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Arthrinic acid was isolated from solid state fermentations of the fungus Arthrinium phaeospermum. The structure of arthrinic acid was determined to be (6E, 10E, 14E, 18E, 20E)-2,3,5,9,13,17-hexahydroxy-20-(hydroxymethyl)- 14,16,1 8,22,24-pentamethylhexacosa-6,10,14,18,20-pentaenoic acid from NMR spectroscopic studies.

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