Journal
JOURNAL OF ANTIBIOTICS
Volume 61, Issue 3, Pages 192-194Publisher
JAPAN ANTIBIOTICS RESEARCH ASSOC
DOI: 10.1038/ja.2008.29
Keywords
marine-derived fungus; sulfoalkylresorcinol; FtsZ
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A new sulfoalkylresorcinol (1) was isolated from the marine-derived Fungus, Zygosporium sp. KNC52. The structure of 1 was elucidated by spectroscopic methods including MS and NMR, and the absolute stereochemistry was determined by the modified Mosher's method. Compound 1 inhibited FtsZ polymerization in vitro and exhibited weak antimicrobial activity against multi-drugresistant bacteria.
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