Journal
JOURNAL OF ANTIBIOTICS
Volume 61, Issue 7, Pages 415-419Publisher
JAPAN ANTIBIOTICS RESEARCH ASSOC
DOI: 10.1038/ja.2008.57
Keywords
marine-derived fungus; Aspergillus sp.; tetrahydrobostrycin; 1-deoxytetrahydrobostrycin; hexahydroanthrone; bostrycin; abscisic acid
Funding
- Grant-in-Aid for Scientific Research on Priority Areas [17035029]
- The Ministry of Education, Culture, Sports, Science and Technology (MEXT)
- Grants-in-Aid for Scientific Research [17035029] Funding Source: KAKEN
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Two new hexahydroanthrones, tetrahydrobostrycin. (1) and 1-deoxytetrahydrobostrycin (2), were isolated from a marine-derived fungus Aspergillus sp. strain 05F16 collected at the coral reef of Manado, Indonesia, together with bostrycin and abscisic acid. The structures of new compounds were determined on the basis of their spectral data. Compound I showed weak antibacterial activity against Staphylococcus aureus and Escherichia coli and 2 against S. aureus.
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