Journal
JOURNAL OF ANALYTICAL CHEMISTRY
Volume 69, Issue 14, Pages 1337-1343Publisher
MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S1061934814140068
Keywords
atenolol; bisoprolol; enalapril; metoprolol; nifedipine; propranolol; GC-MS; artifacts; acute overdose
Categories
Ask authors/readers for more resources
A method is developed for the detection of some antihypertensive drugs, atenolol, bisoprolol, enalapril, metoprolol, nifedipine and propranolol by gas chromatography coupled with mass spectrometry. It is also applicable to screening in clinical toxicology and the identification of both intact APDs and their metabolites. The chances that propranolol, bisoprolol, atenolol, enalapril, and nifedipine form some artifacts in the analysis are assessed. The structures of these compounds are elucidated and a mechanism of their formation in the chromatograph injector is proposed.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available