Journal
JOURNAL OF ALLOYS AND COMPOUNDS
Volume 511, Issue 1, Pages 70-73Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.jallcom.2011.08.043
Keywords
NaYF4; Upconversion; Water soluble; Nanoparticles
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Funding
- National High Technology Research and Development Program of China (863 Program) [2009AA03Z309]
- National Natural Science Foundation of China (NNSFC) [60908031, 51072065]
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Water soluble NaYF4 nanocrystals codoped with 20 mol% Yb3+, 0.5 mol% Tm3+ were prepared by a facile solvothermal approach using polyvinylpyrrolidone (PVP) as a surfactant. The upconversion NaYF4 nanocrystals were pure cubic phase with an average size of similar to 40 nm. They could be well redispersed in water to form a clearly transparent solution without obvious precipitation. With the excitation of a 980-nm diode laser, the nanocrystal solution presents bright violet and blue upconversion luminescence. These upconversion nanoparticles (UCNPs) were incubated with HeLa cells at 37 degrees C for 24 h, and bright blue upconversion luminescence were observed from the UCNPs endocytosed into the HeLa cells on a microscope equipped with a 980-nm fiber laser. These results indicated that the UCNPs had potential applications for biological imaging as luminescent probes. (C) 2011 Elsevier B. V. All rights reserved.
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