Journal
NANOSCALE
Volume 7, Issue 5, Pages 1709-1717Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4nr05908e
Keywords
-
Categories
Funding
- Russian Science Foundation [14-13-01421]
- Government of the Russian Federation [14.Z50.31.0022]
- Russian Foundation for Basic Research [13-04-40228-H]
- Russian Science Foundation [14-13-01421] Funding Source: Russian Science Foundation
Ask authors/readers for more resources
We report a new surface modification approach of upconversion nanoparticles (UCNPs) structured as inorganic hosts NaYF4 codoped with Yb3+ and Er3+ based on their encapsulation in a two-stage process of precipitation polymerization of acrolein under alkaline conditions in the presence of UCNPs. The use of tetramethylammonium hydroxide both as an initiator of acrolein polymerization and as an agent for UCNP hydrophilization made it possible to increase the polyacrolein yield up to 90%. This approach enabled the facile, lossless embedment of UCNPs into the polymer particles suitable for bioassay. These particles are readily dispersible in aqueous and physiological buffers, exhibiting excellent photoluminescence properties, chemical stability, and also allow the control of particle diameters. The feasibility of the as-produced photoluminescent polymer particles mean-sized 260 nm for in vivo optical whole-animal imaging was also demonstrated using a home-built epi-luminescence imaging system.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available