4.8 Article

Can magneto-plasmonic nanohybrids efficiently combine photothermia with magnetic hyperthermia?

Journal

NANOSCALE
Volume 7, Issue 45, Pages 18872-18877

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5nr06168g

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Funding

  1. European Commission [FP7-PEOPLE-2013-IEF-626471]
  2. Institut de Physique (INP) of Centre National de la Recherche Scientifique (CNRS)
  3. Natural Sciences and Engineering Research Council (NSERC), Canada
  4. NSERC
  5. Canada Foundation for Innovation
  6. McMaster University

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Multifunctional hybrid-design nanomaterials appear to be a promising route to meet the current therapeutics needs required for efficient cancer treatment. Herein, two efficient heat nano-generators were combined into a multifunctional single nanohybrid (a multi-core iron oxide nanoparticle optimized for magnetic hyperthermia, and a gold branched shell with tunable plasmonic properties in the NIR region, for photothermal therapy) which impressively enhanced heat generation, in suspension or in vivo in tumours, opening up exciting new therapeutic perspectives.

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