4.8 Review

Photoresponsive nanoparticles for drug delivery

Journal

NANO TODAY
Volume 10, Issue 4, Pages 451-467

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.nantod.2015.06.004

Keywords

Photochemical reaction; Near infrared; Phototriggering; Nanomedicine; Cancer therapy; Nanocarriers

Funding

  1. National Institutes of Health (NIH) [GM073626]
  2. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM073626] Funding Source: NIH RePORTER

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Externally triggerable drug delivery systems provide a strategy for the delivery of therapeutic agents preferentially to a target site, presenting the ability to enhance therapeutic efficacy while reducing side effects. Light is a versatile and easily tuned external stimulus that can provide spatiotemporal control. Here we will review the use of nanoparticles in which light triggers drug release or induces particle binding to tissues (phototargeting). (C) 2015 Elsevier Ltd. All rights reserved.

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