Journal
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Volume 61, Issue 37, Pages 8814-8820Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jf402518k
Keywords
peanut skin; condensed tannin; proanthocyanidin trimer; inhibition on intestinal disaccharidases
Funding
- Government of Inner Mongolia
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Nine compounds including a new A-type proanthocyanidin trimer, epicatechin-(2 beta -> O -> 7,4 beta -> 8)-[catechin-(6 -> 4 beta)]-epicatechin (8), and a known trimer, epicatechin-(4 beta -> 8)-epicatechin-(2 beta -> O -> 7,4 beta -> 8)-catechin (9), being reported for peanut skin for the first time, were isolated and purified. Their structures were determined by spectroscopic methods and by degradation reactions with L-cysteine in acidic conditions. The DPPH radical scavenging activity and the inhibitory activity on maltase and sucrase of the isolated compounds were investigated. All compounds showed strong DPPH scavenging activities (EC50 < 20 mu g/mL). Compound 8 showed the strongest inhibitory activity on maltase with an IC50 value of 0.088 mg/mL, while compound 9 exhibited the strongest inhibition on sucrase with an IC50 value of 0.091 mg/mL.
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