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Anti-hypertensive Nutraceuticals and Functional Foods

Journal

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Volume 57, Issue 11, Pages 4485-4499

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jf900803r

Keywords

ACE; chlorogenic acid; eNOS; fermented milk; fish oil; garlic; ginger; hawthorn; hypertension; L-arginine; onion; tea

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Epidemiological studies have demonstrated that elevated blood pressure is one of the major risk factors for stroke and coronary heart disease (CHID). A close association between blood pressure and the incidence of cardiovascular diseases is well established if systolic/diastolic blood pressure is above 140/90 mmHg. In recent years, nutraceuticals and functional foods have attracted considerable interest as potential alternative therapies for treatment of hypertension, especially for prehypertensive patients, whose blood pressure is marginally or mildly high but not high enough to warrant the prescription of blood pressure-lowering medications. This review summarizes the findings of recent studies on the chemistry, production, application, efficacy, and mechanisms of popular blood pressure-lowering nutraceuticals and functional foods including the Dietary Approaches to Stop Hypertension (DASH) diet plan, L-arginine, chlorogenic acid, fermented milk, garlic, onion, tea, soybean, ginger, hawthorn, and fish oil.

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