Journal
JOURNAL OF AFFECTIVE DISORDERS
Volume 127, Issue 1-3, Pages 199-202Publisher
ELSEVIER
DOI: 10.1016/j.jad.2010.05.023
Keywords
Depression; Personality disorder; Screening interview; Comorbidity
Categories
Funding
- Danish Research Councils [2052-03-0025]
- Center for Pharmacogenomics, University of Copenhagen (Danish Research Councils) [2052-03-0025]
- Lundbeck Foundation [R67-2010-6154] Funding Source: researchfish
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Background: Personality disorder frequently co-occurs with depression and seems to be associated with a poorer outcome of treatment and increased risk for recurrences. However, the diagnosing of personality disorder can be lengthy and requires some training. Therefore, a brief screening interview for comorbid personality disorder among patients suffering from depression would be of clinical use. Method: The present study aimed to assess the utility of the Standardised Assessment of Personality - Abbreviated Scale (SAPAS) as a screen for personality disorder in a population of patients recently diagnosed with first episode depression. A total number of 394 patients with an ICD-10 diagnosis of a single depressive episode were sampled consecutively via the Danish Psychiatric Central Research Register during a 2 years inclusion period and assessed by the screening interview and, subsequently, by the Structured Clinical Interview for DSM-IV Personality Disorders. Results: We found, that a cut-off of 3 on the screen correctly identified the presence of comorbid personality disorder in 73.1% of the patients. The sensitivity and specificity were 0.80 and 0.70, respectively. Limitations: The findings cannot be generalized to patients outside hospital settings. Conclusion: The study provides evidence for the clinical utility of SAPAS as a screening interview for comorbid personality disorder in a population of patients with a primary diagnosis of depression. (C) 2010 Elsevier B.V. All rights reserved.
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