Journal
ANNUAL REVIEW OF NUTRITION, VOL 35
Volume 35, Issue -, Pages 565-594Publisher
ANNUAL REVIEWS
DOI: 10.1146/annurev-nutr-071714-034511
Keywords
carbon-13; nitrogen-15; sulfur-34; nutritional epidemiology; isotope ratio mass spectrometry
Categories
Funding
- NATIONAL CANCER INSTITUTE [R21CA182674] Funding Source: NIH RePORTER
- NATIONAL CENTER FOR RESEARCH RESOURCES [P20RR016430] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [U01GM092676, P30GM103325] Funding Source: NIH RePORTER
- NCI NIH HHS [R21 CA182674] Funding Source: Medline
- NCRR NIH HHS [P20 RR016430] Funding Source: Medline
- NIGMS NIH HHS [U01 GM092676, P30 GM103325] Funding Source: Medline
Ask authors/readers for more resources
Diet is a leading modifiable risk factor for chronic disease, but it remains difficult to measure accurately due to the error and bias inherent in self-reported methods of diet assessment. Consequently, there is a pressing need for more objective biomarkers of diet for use in health research. The stable isotope ratios of light elements are a promising set of candidate biomarkers because they vary naturally and reproducibly among foods, and those variations are captured in molecules and tissues with high fidelity. Recent studies have identified valid isotopic measures of short- and long-term sugar intake, meat intake, and fish intake in specific populations. These studies provide a strong foundation for validating stable isotopic biomarkers in the general US population. Approaches to improve specificity for specific foods are needed; for example, by modeling intake using multiple stable isotope ratios or by isolating and measuring specific molecules linked to foods of interest.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available