Journal
JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT
Volume 6, Issue 3, Pages 210-213Publisher
BLACKWELL PUBLISHING
DOI: 10.1111/j.1610-0387.2007.06546.x
Keywords
cowpox; variola vera; vaccinia immunization; cidofovir; zoonoses; occupational skin disease
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A 21-year-old immunocompetent woman developed a cowpox infection, while working as a veterinarian's assistant in a rural area. She had never received vaccinia immunization and came in contact with a fatally-infected house cat. Under symptomatic treatment, the infection remained localized to one cheek and cleared over 3 weeks with substantial dermal-subcutaneous tissue destruction. Orthopoxvirus detection by PCR is a modern diagnostic standard, in addition to identification by negative-contrast electron microscopy. A promising therapeutic option is ciclofovir, but this virostatic drug is not yet approved for the treatment of cowpox.
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