4.1 Review

Visualization of endolymphatic hydrops with MR imaging in patients with M,niSre's disease and related pathologies: current status of its methods and clinical significance

Journal

JAPANESE JOURNAL OF RADIOLOGY
Volume 32, Issue 4, Pages 191-204

Publisher

SPRINGER
DOI: 10.1007/s11604-014-0290-4

Keywords

Magnetic resonance imaging; Endolymphatic hydrops; Temporal bone disease; Meniere's disease

Funding

  1. Daiichi Sankyo Co. Ltd.
  2. Toshiba Medical Systems Co. Ltd.
  3. Grants-in-Aid for Scientific Research [24659562, 25293263] Funding Source: KAKEN

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Meniere's disease is an inner ear disorder characterized by vertigo attacks, fluctuating low-frequency hearing loss, ear fullness, and tinnitus. Endolymphatic hydrops has long been thought to be the pathological basis for M,niSre's disease. Some patients have inner ear symptoms that do not match the diagnostic guidelines for M,niSre's disease, and these are also thought to be related to endolymphatic hydrops. The diagnosis of endolymphatic hydrops is usually made based on clinical symptoms with some assistance from otological functional tests. Recently, the objective diagnosis of endolymphatic hydrops by MR imaging has become possible and many research results have been reported regarding the imaging methods, evaluation methods, the correlation between imaging results and functional otological tests and the correlation between imaging findings and clinical symptoms. In this article we summarize the development of current imaging methods, evaluation techniques and clinical reports based on a review of the literature. We also attempt to characterize the current significance and future directions of MR imaging of endolymphatic hydrops.

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