Journal
JAPANESE JOURNAL OF RADIOLOGY
Volume 30, Issue 3, Pages 206-217Publisher
SPRINGER
DOI: 10.1007/s11604-011-0033-8
Keywords
Pulmonary nodule; Ground glass opacity; Bronchiolo-alveolar adenocarcinoma; Computed tomography; Follow-up studies
Funding
- Grants-in-Aid for Scientific Research [23591770, 21103008, 22300179] Funding Source: KAKEN
Ask authors/readers for more resources
Purpose To identify the optimum follow-up period for pure ground-glass nodules (GGN) measuring less than 15 mm in diameter, and to evaluate whether the initial HRCT findings can be used as predictors for the progression of pure GGN. Materials and methods A total of 150 pure GGNs present in 111 patients were evaluated. The series of HRCT images for each GGN at the time of the initial detection, 2 years after detection, and at the final follow-up were evaluated. The HRCT findings of GGN were compared between the increasing nodule and non-increasing nodule groups. Results Most (87.3%) pure GGN did not increase whereas some nodules (12.7%) eventually increased after long-term follow-up (mean 66.0 +/- A 25.0 months). Six (31.6%) out of the 19 increasing nodules were regarded as stable at the 2 year follow-up examination. Some morphological findings on initial HRCT, including a size greater than 10 mm (p = 0.001), lobulated margins (p = 0.015), and a bubble-like appearance (p = 0.002), were significantly associated with the growth of pure GGNs. Conclusion More than 2 years of follow-up are necessary to detect the growth of pure GGNs. Some characteristic findings indicated a high likelihood of future growth of the GGN.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available