Journal
MOLECULES
Volume 20, Issue 4, Pages 6715-6738Publisher
MDPI
DOI: 10.3390/molecules20046715
Keywords
biological activity; biosynthesis; Calycanthaceae alkaloids; structure; synthesis
Funding
- National Natural Science Foundation of China [81303305]
- Major Science & Technology Project of Zhejiang Province [2012C12014-1]
- Lishui Science & Technology Bureau Research Fund [20140212037]
- Lishui Agricultural Bureau Research Fund [LS20140010]
Ask authors/readers for more resources
Plants of the Calycanthaceae family, which possesses four genera and about 15 species, are mainly distributed in China, North America and Australia. Chemical studies on the Calycanthaceae have led to the discovery of about 14 alkaloids of different skeletons, including dimeric piperidinoquinoline, dimeric pyrrolidinoindoline and/or trimeric pyrrolidinoindolines, which exhibit significant anti-convulsant, anti-fungal, anti-viral analgesic, anti-tumor, and anti-melanogenesis activities. As some of complex tryptamine-derived alkaloids exhibit promising biological activities, the syntheses of these alkaloids have also been a topic of interest in synthetic chemistry during the last decades. This review will focus on the structures and total syntheses of these alkaloids.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available