Journal
MOLECULES
Volume 20, Issue 9, Pages 17339-17361Publisher
MDPI
DOI: 10.3390/molecules200917339
Keywords
palm oil; palmitic acid; obesity; T2DM; cardiovascular diseases; cancer; SFA; TAG; PUFA; MUFA
Funding
- CEINGE Regione Campania [DGRC 1901/2009]
- IRCCS SDN
- Ministry of Health
- POR Campania FSE [2007-2013-CUP B25B09000050007]
- Project CREME
- [PON02_00619_3461281]
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A growing body of evidence highlights the close association between nutrition and human health. Fat is an essential macronutrient, and vegetable oils, such as palm oil, are widely used in the food industry and highly represented in the human diet. Palmitic acid, a saturated fatty acid, is the principal constituent of refined palm oil. In the last few decades, controversial studies have reported potential unhealthy effects of palm oil due to the high palmitic acid content. In this review we provide a concise and comprehensive update on the functional role of palm oil and palmitic acid in the development of obesity, type 2 diabetes mellitus, cardiovascular diseases and cancer. The atherogenic potential of palmitic acid and its stereospecific position in triacylglycerols are also discussed.
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